Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 16/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.48 |
| ▸ | NQO2 | P16083 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627326 | 0.87 | MTNR1A (0.48) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL8627320 | 0.83 | MTNR1A (0.50) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL8830018 | 0.79 | MEN1 (0.39) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8625156 | 0.78 | KDM4E (0.50) | MTNR1AMTNR1BNQO2TDP1L3MBTL1 | |
| SCHEMBL8599327 | 0.75 | SLC6A4 (0.52) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8623913 | 0.73 | KDM4E (0.46) | MTNR1AMTNR1BNQO2TDP1L3MBTL1 | |
| SCHEMBL8626999 | 0.70 | MTNR1A (0.41) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL8830126 | 0.69 | AKR1C3 (0.35) | NQO2NPC1RAB9A | |
| SCHEMBL8623636 | 0.66 | ALDH1A1 (0.41) | MTNR1AMTNR1BTDP1 | |
| SCHEMBL7958710 | 0.66 | PTGIR (0.64) | MTNR1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657422-A1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | disclosed |