Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9229411 | 0.92 | PAM (0.42) | PAMMAOBALDH1A1HPGDMAOA | |
| SCHEMBL9232304 | 0.84 | PAM (0.44) | PAMMAOBALDH1A1HPGDMAOA | |
| SCHEMBL9233464 | 0.81 | PAM (0.41) | PAMMAOBALDH1A1HPGDMAOA | |
| SCHEMBL8828415 | 0.72 | PAM (0.58) | PAMMAOBALDH1A1MEN1MAPT | |
| SCHEMBL8828409 | 0.72 | PAM (0.58) | PAMMAOBALDH1A1MEN1MAPT | |
| SCHEMBL9212612 | 0.72 | KMT2A (0.56) | PAMMAOBALDH1A1MEN1MAPT | |
| SCHEMBL9213200 | 0.71 | KDM4C (0.49) | PAMMAOBALDH1A1MEN1MAPT | |
| SCHEMBL9213867 | 0.70 | PAM (0.54) | PAMMAOBALDH1A1MAOAMEN1 | |
| SCHEMBL9282635 | 0.70 | PAM (0.44) | PAMMAOBALDH1A1HPGDMAOA | |
| SCHEMBL9210792 | 0.68 | PAM (0.51) | PAMMAOBALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633248-A1 | Butenoic acid derivatives | Eisai Co., Ltd. (JP) | 1995-01-11 | — | — | EP | disclosed |
| EP-0589491-A1 | Butenoic acid derivatives | Eisai Co., Ltd. (JP) | 1994-03-30 | — | — | EP | disclosed |
| EP-0399358-A2 | Butenoic acid derivatives | Eisai Co., Ltd. (JP) | 1990-11-28 | — | — | EP | disclosed |