Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | F2R | P25116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10470440 | 0.87 | MAOB (0.34) | MAOBMAOAACHEGAAALDH1A1 | |
| SCHEMBL9230351 | 0.86 | ALDH1A1 (0.38) | MAOBMAOAACHEGAAALDH1A1 | |
| SCHEMBL10470627 | 0.86 | MAOB (0.38) | MAOBMAOAACHEGAAALDH1A1 | |
| SCHEMBL10470534 | 0.85 | GAA (0.38) | MAOBMAOAACHEGAAALDH1A1 | |
| SCHEMBL9230983 | 0.85 | GAA (0.35) | MAOBMAOAACHEGAAALDH1A1 | |
| SCHEMBL9227024 | 0.84 | GAA (0.34) | MAOBMAOAACHEGAAALDH1A1 | |
| SCHEMBL9871543 | 0.84 | GAA (0.39) | MAOBMAOAACHEGAAALDH1A1 | |
| SCHEMBL9869698 | 0.83 | GAA (0.38) | MAOBMAOAACHEGAAALDH1A1 | |
| SCHEMBL10135978 | 0.83 | ALOX5 (0.44) | MAOBMAOAACHEGAAALDH1A1 | |
| SCHEMBL9228497 | 0.83 | GAA (0.35) | MAOBMAOAACHEGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5476882-A | Containing 2,2,6,6-tetraalkylpiperidine derivative | CIBA-GEIGY CORPORATION (US) | 1995-12-19 | — | — | US | disclosed |
| US-5274016-A | Crosslinked polyolefin core and stabilizer of a 2,2,6,6-tetramethylpiperidine derivative having at least one ethylenic double bone | CIBA-GEIGY CORPORATION (US) | 1993-12-28 | — | — | US | disclosed |
| US-4894399-A | Light-stabilized polymer microparticles containing epoxy groups | CIBA-GEIGY CORPORATION (US) | 1990-01-16 | — | — | US | disclosed |