Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5537083 | 0.75 | PDPK1 (0.52) | PDPK1ADRA1AADRA1DADRA1BCASP6 | |
| SCHEMBL10448407 | 0.75 | PDPK1 (0.44) | PDPK1HSD17B10ADRA1AADRA1DADRA1B | |
| SCHEMBL9062692 | 0.74 | CSNK1A1 (0.41) | ADRA1ACASP6HTR7ADRA2AALDH1A1 | |
| SCHEMBL4815940 | 0.73 | HTR7 (0.51) | HTR7FBP1 | |
| SCHEMBL5014843 | 0.70 | PDPK1 (0.48) | PDPK1ADRA1AADRA1DADRA1BCASP6 | |
| SCHEMBL3283302 | 0.69 | PDPK1 (0.39) | PDPK1ADRA1AADRA1DADRA1BCASP6 | |
| SCHEMBL9263308 | 0.69 | PDPK1 (0.44) | PDPK1ADRA1AADRA1DADRA1BCASP6 | |
| Hydrochloric Acid SCHEMBL9231141 | 0.68 | MAOA (0.47) | PDPK1ADRA1AADRA1DADRA1BRAB9A | |
| Hydrochloric Acid SCHEMBL9223808 | 0.68 | MAOA (0.47) | PDPK1ADRA1AADRA1DADRA1BRAB9A | |
| SCHEMBL5692672 | 0.68 | PDPK1 (0.64) | PDPK1HSD17B10ADRA1AADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995019352-A3 | PROCESS FOR THE PREPARATION OF 2-(4,4-DIFLUORO-BUT-3-ENYLTHIO)-BENZ-THIAZOLES AND -BENZOXAZOLES | ZENECA LTD (GB) | 1996-01-18 | — | — | WO | disclosed |
| WO-1995019352-A2 | PROCESS FOR THE PREPARATION OF 2-(4,4-DIFLUORO-BUT-3-ENYLTHIO)-BENZ-THIAZOLES AND -BENZOXAZOLES | ZENECA LIMITED (GB) | 1995-07-20 | — | — | WO | disclosed |