Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | LCAT | P04180 | 2/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718390 | 0.92 | HTT (0.50) | HTTGPR119POLBL3MBTL1PPARD | |
| SCHEMBL8723261 | 0.83 | ACACB (0.41) | HTTGPR119MAPTTDP1CACNA1G | |
| SCHEMBL8718833 | 0.80 | POLB (0.56) | HTTGPR119POLBL3MBTL1PPARD | |
| SCHEMBL3117217 | 0.79 | MAPT (0.52) | L3MBTL1MAPTTDP1 | |
| SCHEMBL6174527 | 0.74 | HTT (0.46) | HTTGPR119POLBL3MBTL1MAPT | |
| SCHEMBL29945199 | 0.74 | GAA (0.48) | HTTGPR119MAPTTDP1 | |
| SCHEMBL14884466 | 0.74 | GPR119 (0.48) | HTTGPR119MAPT | |
| SCHEMBL7190990 | 0.74 | KCNA5 (0.36) | PPARDPPARAMAPTKCNA5CACNA1G | |
| SCHEMBL20639686 | 0.74 | GPR119 (0.48) | HTTGPR119MAPTMMP13 | |
| SCHEMBL3937241 | 0.74 | ADRB1 (0.56) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659751-A1 | Optically active azole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-06-28 | — | — | EP | disclosed |