Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 1/20 | 0.46 |
| ▸ | SELE | P16581 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726514 | 0.88 | PTGER2 (0.46) | P2RX3KDM1ALMNAL3MBTL1PIN1 | |
| SCHEMBL8722252 | 0.81 | MAPT (0.59) | LMNAL3MBTL1PIN1KDM4EMEN1 | |
| SCHEMBL8724307 | 0.81 | L3MBTL1 (0.57) | P2RX3LMNAL3MBTL1KDM4EMEN1 | |
| SCHEMBL9233259 | 0.81 | MAPT (0.49) | ICAM1SELECHEK2L3MBTL1PIN1 | |
| SCHEMBL9237096 | 0.78 | SLC6A2 (0.43) | P2RX3LMNAL3MBTL1SCN9AALDH1A1 | |
| SCHEMBL29654005 | 0.71 | KDM1A (0.78) | KDM1ALMNAL3MBTL1KDM4EMEN1 | |
| SCHEMBL28707161 | 0.71 | KDM1A (0.78) | KDM1ALMNAL3MBTL1KDM4EMEN1 | |
| SCHEMBL5343234 | 0.70 | KDM4E (0.45) | P2RX3LMNAL3MBTL1ACHEKDM4E | |
| SCHEMBL11588419 | 0.70 | P2RX3 (0.55) | P2RX3MAPT | |
| SCHEMBL28192184 | 0.68 | HTR2B (0.44) | P2RX3LMNAHTR2BACHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700394-A1 | HERBICIDAL THIAZOLE DERIVATIVES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027983-A1 | HERBICIDAL THIAZOLE DERIVATIVES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1994-12-08 | — | — | WO | disclosed |