SCHEMBL923356

SCHEMBL923356

Nc1ncccc1C(=O)NCc1cccc(OCc2ccccc2F)c1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.49
HPGD P15428 2/20 0.49
ALDH1A1 P00352 2/20 0.49
LMNA P02545 1/20 0.49
KDM4E B2RXH2 1/20 0.49
USP2 O75604 1/20 0.49
MAPK8 P45983 2/20 0.47
MEN1 O00255 2/20 0.45
POLB P06746 1/20 0.45
MAPT P10636 1/20 0.45
RAB9A P51151 2/20 0.44
NPC1 O15118 1/20 0.44
NSD2 O96028 1/20 0.44
KLKB1 P03952 1/20 0.44
SCN3A Q9NY46 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1681273 0.89 SCN3A (0.56) KMT2AHPGDLMNAMAPK8MEN1
SCHEMBL920847 0.88 HPGD (0.52) KMT2AHPGDALDH1A1KDM4EUSP2
SCHEMBL919787 0.87 MAPK8 (0.56) KMT2AHPGDALDH1A1KDM4EUSP2
SCHEMBL921619 0.86 HPGD (0.55) KMT2AHPGDALDH1A1LMNAKDM4E
SCHEMBL921514 0.86 LMNA (0.55) KMT2AHPGDALDH1A1LMNAKDM4E
SCHEMBL923100 0.86 HPGD (0.51) KMT2AHPGDALDH1A1KDM4EUSP2
SCHEMBL919713 0.85 MAPK8 (0.51) KMT2AHPGDALDH1A1KDM4EUSP2
SCHEMBL922884 0.83 MAPK8 (0.56) KMT2AHPGDALDH1A1KDM4EUSP2
SCHEMBL921909 0.82 KMT2A (0.66) KMT2AHPGDALDH1A1LMNAKDM4E
SCHEMBL923219 0.82 HPGD (0.67) KMT2AHPGDALDH1A1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 KMT2A 2469/4885HPGD 1273/4885ALDH1A1 2743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.