Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TXN | P10599 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9229979 | 0.76 | CYP1A2 (0.45) | POLBSMN1; SMN2MAPTLMNANPC1 | |
| SCHEMBL9232603 | 0.76 | LMNA (0.45) | POLBSMN1; SMN2MAPTLMNARAB9A | |
| SCHEMBL12368481 | 0.72 | POLB (1.00) | POLBSMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL9233968 | 0.71 | POLB (0.49) | POLBSMN1; SMN2MAPTLMNARAB9A | |
| SCHEMBL29888697 | 0.69 | SMN1; SMN2 (0.71) | POLBSMN1; SMN2MAPTLMNARAB9A | |
| SCHEMBL10644621 | 0.69 | POLB (0.69) | POLBSMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL11687997 | 0.69 | POLB (0.63) | POLBSMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL9514715 | 0.67 | POLB (0.71) | POLBSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL7066256 | 0.67 | TXN (0.55) | POLBSMN1; SMN2MAPTLMNARAB9A | |
| SCHEMBL9676986 | 0.67 | POLB (0.60) | POLBSMN1; SMN2RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632040-A1 | Antibacterial imidazole derivatives | Takeda Chemical Industries, Ltd. (JP) | 1995-01-04 | — | — | EP | disclosed |