Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | TXN | P10599 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12368481 | 0.83 | POLB (1.00) | POLBSMN1; SMN2RAB9ANPC1BCHE | |
| SCHEMBL9512665 | 0.80 | POLB (0.65) | POLBSMN1; SMN2RAB9ANPC1BCHE | |
| SCHEMBL9676986 | 0.77 | POLB (0.60) | POLBSMN1; SMN2RAB9ANPC1BCHE | |
| SCHEMBL10644621 | 0.76 | POLB (0.69) | POLBSMN1; SMN2RAB9ANPC1BCHE | |
| SCHEMBL10352132 | 0.73 | POLB (0.70) | POLBSMN1; SMN2RAB9ANPC1BCHE | |
| SCHEMBL29367169 | 0.73 | POLB (0.65) | POLBSMN1; SMN2RAB9ANPC1BCHE | |
| SCHEMBL374735 | 0.73 | POLB (0.65) | POLBSMN1; SMN2RAB9ANPC1BCHE | |
| SCHEMBL11687997 | 0.73 | POLB (0.63) | POLBSMN1; SMN2RAB9ANPC1BCHE | |
| SCHEMBL159798 | 0.73 | TXN (0.72) | POLBSMN1; SMN2RAB9ANPC1BCHE | |
| SCHEMBL3792726 | 0.73 | BCHE (0.68) | POLBSMN1; SMN2RAB9ANPC1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0334818-B1 | Pharmacologically active alkylthiobenz imidazole derivatives and process for the preparation thereof | DOMPE FARMACEUTICI SPA (IT) | 1993-12-01 | — | — | EP | disclosed |
| US-4983620-A | ANTIHISTAMINES, ANTIALLERGENS | DOMPE FARMACEUTICI S.P.A. (IT) | 1991-01-08 | — | — | US | disclosed |