Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.48 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | IL6 | P05231 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9237045 | 0.99 | HDAC6 (0.49) | HDAC6SSTR1SSTR5HDAC3HDAC1 | |
| SCHEMBL9234640 | 0.86 | HDAC6 (0.45) | HDAC6HDAC3HDAC1HDAC8RAB9A | |
| SCHEMBL9230872 | 0.86 | MAPT (0.48) | HDAC6HDAC3HDAC1HDAC8NPC1 | |
| SCHEMBL7540148 | 0.74 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL27756459 | 0.72 | HDAC6 (0.49) | HDAC6SSTR1SSTR5HDAC3HDAC1 | |
| SCHEMBL31430548 | 0.72 | HDAC6 (0.62) | HDAC6HDAC3HDAC1HDAC8NPC1 | |
| SCHEMBL2841557 | 0.72 | TTR (0.49) | HDAC6SSTR5NPC1RAB9AHPGD | |
| SCHEMBL5364592 | 0.71 | THRB (0.57) | HDAC6HDAC1MBOAT4KCNH2MEN1 | |
| SCHEMBL31430456 | 0.71 | HDAC6 (0.54) | HDAC6HDAC3HDAC1HDAC8KCNH2 | |
| SCHEMBL21066322 | 0.71 | HDAC6 (0.52) | HDAC6HDAC3HDAC1HDAC8NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665461-A1 | Photographic sensitivity increasing alkynylamine compounds and photographic elements | EASTMAN KODAK COMPANY (US) | 1995-08-02 | — | — | EP | disclosed |
| US-5413905-A | High speed | EASTMAN KODAK COMPANY (US) | 1995-05-09 | — | — | US | disclosed |