Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 20/20 | 0.57 |
| ▸ | DRD2 | P14416 | 12/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829503 | 0.81 | SIGMAR1 (0.40) | SIGMAR1DRD2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8700031 | 0.79 | SIGMAR1 (0.53) | SIGMAR1DRD2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL7829992 | 0.79 | SIGMAR1 (0.47) | SIGMAR1DRD2 | |
| SCHEMBL7832946 | 0.79 | CYP2A6 (0.44) | SIGMAR1 | |
| SCHEMBL28042699 | 0.78 | BACE1 (0.50) | SIGMAR1DRD2 | |
| SCHEMBL9235508 | 0.74 | SIGMAR1 (0.47) | SIGMAR1DRD2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL357523 | 0.72 | SIGMAR1 (0.49) | SIGMAR1DRD2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8905733 | 0.72 | SIGMAR1 (0.51) | SIGMAR1DRD2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL6993020 | 0.68 | RARA (0.43) | SIGMAR1DRD2 | |
| SCHEMBL37303 | 0.67 | CFTR (0.44) | SIGMAR1DRD2GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1166658-C | 4,5 diaryl-3 (2H) -furanone derivatives as cyclooxygenase-2 inhibitors | ��ʽ����̫ƽ�� | 2004-09-15 | — | — | CN | disclosed |
| CN-1348447-A | 4,5 diaryl-3 (2H) -furanone derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORP (KR) | 2002-05-08 | — | — | CN | disclosed |