Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9692997 | 0.90 | EGFR (0.50) | MEN1LMNAHTTKMT2AEGFR | |
| SCHEMBL9692973 | 0.78 | EGFR (0.54) | MEN1LMNAHTTKMT2AEGFR | |
| SCHEMBL22521780 | 0.77 | LMNA (0.77) | MEN1LMNAHTTKMT2AEGFR | |
| SCHEMBL9123290 | 0.76 | SMN1; SMN2 (0.53) | MEN1LMNAHTTKMT2A | |
| SCHEMBL9122575 | 0.74 | PTGES (0.55) | MEN1LMNAKMT2ATDP1 | |
| SCHEMBL22521650 | 0.74 | MEN1 (0.98) | MEN1LMNAHTTKMT2AEGFR | |
| SCHEMBL24559136 | 0.73 | MEN1 (0.80) | MEN1LMNAHTTKMT2AEGFR | |
| SCHEMBL22521653 | 0.73 | LMNA (0.80) | MEN1LMNAHTTKMT2AEGFR | |
| SCHEMBL9124575 | 0.73 | MAPT (0.42) | MEN1LMNAHTTKMT2AALDH1A1 | |
| SCHEMBL22521651 | 0.71 | LMNA (0.76) | MEN1LMNAHTTKMT2AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470858-A | Anticholesterol agents | PIERREL SPA (IT) | 1995-11-28 | — | — | US | disclosed |