Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9238191 | 0.90 | MEN1 (0.57) | EGFRMEN1LMNAHTTKMT2A | |
| SCHEMBL9692973 | 0.86 | EGFR (0.54) | EGFRMEN1LMNAHTTKMT2A | |
| SCHEMBL9241071 | 0.78 | ALDH1A1 (0.48) | MEN1LMNAHTTKMT2AALDH1A1 | |
| SCHEMBL9693206 | 0.77 | SMN1; SMN2 (0.52) | MEN1LMNAHTTKMT2AALDH1A1 | |
| SCHEMBL9222642 | 0.74 | PTGES (0.47) | LMNAKMT2A | |
| SCHEMBL9693067 | 0.73 | TSHR (0.41) | MEN1LMNAKMT2AALDH1A1MAPK1 | |
| SCHEMBL9124612 | 0.72 | MAPT (0.51) | LMNAHTTKMT2AALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL9124078 | 0.71 | RAB9A (0.47) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9690566 | 0.71 | GAA (0.45) | MEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL9693018 | 0.70 | RAB9A (0.62) | MEN1LMNAKMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520552-A1 | Derivatives of (hetero) aromatic ethers and thioethers having antihyperlipidemic activity, process for their preparation and pharmaceutical compositions containing them | PIERREL S.p.A. (IT) | 1992-12-30 | — | — | EP | claimed |
| EP-0520552-A1 | Derivatives of (hetero) aromatic ethers and thioethers having antihyperlipidemic activity, process for their preparation and pharmaceutical compositions containing them | PIERREL S.p.A. (IT) | 1992-12-30 | — | — | EP | disclosed |