Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9222642 | 0.90 | PTGES (0.47) | PTGESKDM4ELMNAMAPTHPGD | |
| SCHEMBL9123290 | 0.82 | SMN1; SMN2 (0.53) | KDM4ELMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL9123641 | 0.80 | LMNA (0.48) | KDM4ELMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL9124626 | 0.76 | RAB9A (0.63) | KDM4ELMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL9212087 | 0.76 | KDM4E (0.63) | PTGESKDM4ELMNAMAPTHPGD | |
| SCHEMBL9124575 | 0.75 | MAPT (0.42) | KDM4ELMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL9238191 | 0.74 | MEN1 (0.57) | LMNAKMT2AMEN1TDP1 | |
| SCHEMBL9663630 | 0.73 | KDM4E (0.65) | PTGESKDM4ELMNAMAPTHPGD | |
| SCHEMBL9125191 | 0.73 | MAPT (0.47) | LMNAMAPTKMT2A | |
| SCHEMBL9665899 | 0.72 | KDM4E (0.53) | PTGESKDM4ELMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470858-A | Anticholesterol agents | PIERREL SPA (IT) | 1995-11-28 | — | — | US | disclosed |