Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | F9 | P00740 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL927638 | 0.77 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL3640667 | 0.76 | KDM4E (0.52) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL30565424 | 0.75 | TSHR (0.53) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL9204703 | 0.72 | L3MBTL1 (0.54) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL7323723 | 0.70 | TDP1 (0.56) | ALDH1A1MEN1KMT2ATDP1HPGD | |
| SCHEMBL3407190 | 0.70 | MTNR1A (0.46) | ALDH1A1KDM4EPRMT5 | |
| SCHEMBL628126 | 0.69 | KMT2A (0.53) | MEN1KMT2AMAPTTDP1LMNA | |
| SCHEMBL9205212 | 0.69 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL10390030 | 0.69 | TSHR (0.51) | ALDH1A1MEN1KMT2ATDP1HPGD | |
| SCHEMBL9204917 | 0.69 | TSHR (0.44) | ALDH1A1MEN1KMT2AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663397-A2 | Bicyclic heteroaryl compounds, process for their preparation and their use as safener | Hoechst Schering AgrEvo GmbH (DE) | 1995-07-19 | — | — | EP | disclosed |