Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.33 |
| ▸ | GMNN | O75496 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | BLM | P54132 | 3/20 | 0.33 |
| ▸ | CETP | P11597 | 3/20 | 0.33 |
| ▸ | UBE2N | P61088 | 3/20 | 0.33 |
| ▸ | THPO | P40225 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10910541 | 0.76 | LMNA (0.41) | CYP2D6MAPTSPHK1GMNNLMNA | |
| SCHEMBL31738650 | 0.76 | CYP2D6 (0.38) | CYP2D6MAPTSPHK1GMNNLMNA | |
| SCHEMBL29199484 | 0.76 | CYP2D6 (0.38) | CYP2D6MAPTSPHK1GMNNLMNA | |
| SCHEMBL6006803 | 0.74 | CYP2D6 (0.41) | CYP2D6MAPTSPHK1GMNNLMNA | |
| SCHEMBL6892245 | 0.72 | FDPS (0.33) | CYP2D6MAPTSPHK1GMNNLMNA | |
| SCHEMBL6048321 | 0.70 | PAX8 (0.39) | PAX8 | |
| SCHEMBL1092322 | 0.70 | PAX8 (0.39) | PAX8 | |
| SCHEMBL29169784 | 0.69 | MGAM (0.38) | ALDH1A1 | |
| SCHEMBL5841129 | 0.68 | PAX8 (0.33) | PAX8 | |
| SCHEMBL29169771 | 0.68 | USP2 (0.51) | MAPTSPHK1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995031998-A1 | CANDIDA ALBICANS ADHESIN AS A VACCINE | THE RESEARCH & DEVELOPMENT INSTITUTE, INC. (US) | 1995-11-30 | — | — | WO | disclosed |
| US-4868155-A | IMMUNE SYSTEM STIMULANTS | MERCK & CO., INC. (US) | 1989-09-19 | — | — | US | disclosed |
| EP-0038750-A1 | Immunologically active dipeptidyl 4-0-, 6-0-acyl-2-amino-2-deoxy-D-glucose derivatives and methods for their preparation | MERCK & CO. INC. (US) | 1981-10-28 | — | — | EP | disclosed |