SCHEMBL5841129

SCHEMBL5841129

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nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PAX8 Q06710 1/20 0.33
AKR1B1 P15121 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL458801 0.80 AKR1B1 (0.36) AKR1B1
SCHEMBL30500659 0.80 AKR1B1 (0.36) AKR1B1
SCHEMBL31757604 0.80 AKR1B1 (0.36) AKR1B1
SCHEMBL22692164 0.77 AKR1B1 (0.40) AKR1B1
SCHEMBL310198 0.77 AKR1B1 (0.40) AKR1B1
SCHEMBL6048321 0.76 PAX8 (0.39) PAX8AKR1B1
SCHEMBL1092322 0.76 PAX8 (0.39) PAX8AKR1B1
SCHEMBL9274321 0.73 FDPS (0.32) PAX8AKR1B1
SCHEMBL5841143 0.70 TP53 (0.30)
SCHEMBL31630521 0.69 TDP1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600740-B2 Fluorinated N-acetyl glucosamine analogs and xylose derivatives UTI LIMITED PARTNERSHIP (CA) 2026-04-14 US disclosed
US-12227788-B2 Compositions, methods and treatments for inhibiting cell adhesion and virus binding and penetration TUMOREND, LLC (US) 2025-02-18 US disclosed
US-11787844-B2 Targeting of chondroitin sulfate glycans VAR2 PHARMACEUTICALS APS (DK) 2023-10-17 US disclosed
US-20220396823-A1 COMPOSITIONS, METHODS AND TREATMENTS FOR INHIBITING CELL ADHESION AND VIRUS BINDING AND PENETRATION TUMOREND, LLC (US) 2022-12-15 US disclosed
US-20220332746-A1 FLUORINATED N-ACETYL GLUCOSAMINE ANALOGS AND XYLOSE DERIVATIVES UTI LIMITED PARTNERSHIP (CA) 2022-10-20 US disclosed
US-11365212-B2 Fluorinated N-acetyl glucosamine analogs and xylose derivatives UTI LIMITED PARTNERSHIP (CA) 2022-06-21 US disclosed
US-11203776-B2 Compositions, methods and treatments for inhibiting cell adhesion and virus binding and penetration TUMOREND, LLC (US) 2021-12-21 US disclosed
EP-3087091-B1 VAR2CSA-DRUG CONJUGATES ZYMEWORKS INC (CA) 2021-10-20 EP disclosed
US-20210214384-A1 FLUORINATED N-ACETYL GLUCOSAMINE ANALOGS AND XYLOSE DERIVATIVES UTI LIMITED PARTNERSHIP (CA) 2021-07-15 US disclosed
CN-104136041-B Targeted chondroitin sulfate glycans VAR2制药有限公司 2021-06-29 CN disclosed
WO-2015095952-A1 VAR2CSA-DRUG CONJUGATES THE CENTRE FOR DRUG RESEARCH AND DEVELOPMENT (CA) 2015-07-02 WO disclosed
US-20150004099-A1 TARGETING OF CHONDROITIN SULFATE GLYCANS VAR2 PHARMACEUTICALS APS (DK) 2015-01-01 US disclosed
EP-2812024-A1 TARGETING OF CHONDROITIN SULFATE GLYCANS Var2 Pharmaceuticals ApS (DK) 2014-12-17 EP disclosed
WO-2013117705-A1 TARGETING OF CHONDROITIN SULFATE GLYCANS VAR2 PHARMACEUTICALS APS (DK) 2013-08-15 WO disclosed
US-20060281708-A1 Fluorinated glucosamine analogs useful for modulating post-translational glyscosylations on cells THE BRIGHAM AND WOMEN'S HOSPITAL, INC. 2006-12-14 US disclosed
US-7098195-B2 Fluorinated glucosamine analogs useful for modulating post-translational glycosylations on cells HEALTH RESEARCH, INC. (US) 2006-08-29 US disclosed
EP-1461046-A4 FLUORINATED GLUCOSAMINE ANALOGS USEFUL FOR MODULATING POST-TRANSLATIONAL GLYCOSYLATIONS ON CELLS BRIGHAM & WOMENS HOSPITAL (US) 2005-06-22 EP disclosed
EP-1461046-A2 FLUORINATED GLUCOSAMINE ANALOGS USEFUL FOR MODULATING POST-TRANSLATIONAL GLYCOSYLATIONS ON CELLS THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2004-09-29 EP disclosed
WO-2003093410-A2 FLUORINATED GLUCOSAMINE ANALOGS USEFUL FOR MODULATING POST-TRANSLATIONAL GLYCOSYLATIONS ON CELLS THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2003-11-13 WO disclosed
US-20030148997-A1 Fluorinated glucosamine analogs useful for modulating post-translational glycosylations on cells NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220396823-A1 COMPOSITIONS, METHODS AND TREATMENTS FOR INHIBITING CELL ADHESION AND VIRUS BINDING AND PENETRATION SIGLEC7, SIGLEC9, HAVCR2 PAX8 4718/4885AKR1B1 2345/4885
US-11203776-B2 Compositions, methods and treatments for inhibiting cell adhesion and virus binding and penetration SIGLEC7, SIGLEC9, HAVCR2 PAX8 4718/4885AKR1B1 2345/4885
US-11365212-B2 Fluorinated N-acetyl glucosamine analogs and xylose derivatives FUT6, FUT5, B3GNT2 PAX8 1990/4885AKR1B1 1989/4885
US-20060281708-A1 Fluorinated glucosamine analogs useful for modulating post-translational glyscosylations on cells B3GAT3, UGGT1, FUT5 PAX8 4248/4885AKR1B1 3448/4885
US-20220332746-A1 FLUORINATED N-ACETYL GLUCOSAMINE ANALOGS AND XYLOSE DERIVATIVES CSGALNACT1, FUT6, FUT5 PAX8 2233/4885AKR1B1 3454/4885
US-12600740-B2 Fluorinated N-acetyl glucosamine analogs and xylose derivatives CSGALNACT1, FUT5, FUT6 PAX8 2953/4885AKR1B1 3339/4885
US-12227788-B2 Compositions, methods and treatments for inhibiting cell adhesion and virus binding and penetration SIGLEC7, SIGLEC9, HAVCR2 PAX8 4718/4885AKR1B1 2345/4885
US-20030148997-A1 Fluorinated glucosamine analogs useful for modulating post-translational glycosylations on cells FUT5, FUT6, OGT PAX8 4397/4885AKR1B1 3044/4885
US-20210214384-A1 FLUORINATED N-ACETYL GLUCOSAMINE ANALOGS AND XYLOSE DERIVATIVES FUT6, FUT5, B3GNT2 PAX8 1990/4885AKR1B1 1989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.