SCHEMBL9240201

SCHEMBL9240201

O=C(O)Oc1ccc2cc3ccccc3nc2c1OC(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
MAPT P10636 2/20 0.40
HPGD P15428 2/20 0.40
GLA P06280 1/20 0.40
ACHE P22303 1/20 0.40
MGAM O43451 2/20 0.40
CNR2 P34972 1/20 0.36
KDM4E B2RXH2 4/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HTR3A P46098 1/20 0.36
IKBKB O14920 1/20 0.36
RAB9A P51151 5/20 0.35
NPC1 O15118 4/20 0.35
NPSR1 Q6W5P4 2/20 0.35
PRNP P04156 1/20 0.35
MAPK10 P53779 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
LMNA P02545 2/20 0.35
NFKB1 P19838 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7826659 0.75 ALDH1A1 (0.42) ALDH1A1MAPTHPGDGLAKDM4E
SCHEMBL377229 0.74 LMNA (0.50) ALDH1A1MAPTHPGDKDM4EMEN1
SCHEMBL8127607 0.73 ALDH1A1 (0.43) ALDH1A1MAPTHPGDGLAACHE
SCHEMBL7534418 0.73 ALDH1A1 (0.42) ALDH1A1MAPTHPGDGLAACHE
SCHEMBL7068984 0.73 NCEH1 (0.45) ALDH1A1MAPTHPGDKDM4ERAB9A
SCHEMBL1723471 0.72 MAPT (0.46) ALDH1A1MAPTHPGDGLAACHE
SCHEMBL10504538 0.72 SMN1; SMN2 (0.56) ALDH1A1MAPTHPGDGLAACHE
SCHEMBL2923055 0.72 NQO2 (0.55) ALDH1A1MAPTHPGDGLAACHE
SCHEMBL4902020 0.71 ALDH1A1 (0.70) ALDH1A1MAPTHPGDGLAACHE
SCHEMBL294784 0.71 MGAM (0.53) ALDH1A1MAPTMGAMCNR2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0683212-A1 New dyes for the bulk dyeing of synthetic materials BAYER AG (DE) 1995-11-22 EP disclosed