Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 8/20 | 0.55 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28215106 | 0.83 | TLR8 (0.56) | NQO2TLR8NPC1RAB9AKDM4E | |
| SCHEMBL6239156 | 0.81 | NQO2 (0.67) | NQO2TLR8NPC1RAB9AKDM4E | |
| SCHEMBL30228371 | 0.81 | NQO2 (0.67) | NQO2TLR8NPC1RAB9AKDM4E | |
| SCHEMBL7755602 | 0.77 | NQO2 (0.67) | NQO2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL9755341 | 0.77 | POLB (0.55) | NQO2TLR8NPC1RAB9AKDM4E | |
| SCHEMBL6972381 | 0.76 | NQO2 (0.63) | NQO2TLR8NPC1RAB9AKDM4E | |
| SCHEMBL4902020 | 0.75 | ALDH1A1 (0.70) | NQO2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL16671109 | 0.72 | POLB (0.48) | NQO2TLR8NPC1RAB9AKDM4E | |
| SCHEMBL29977206 | 0.72 | POLB (0.48) | NQO2TLR8NPC1RAB9AKDM4E | |
| SCHEMBL4916091 | 0.72 | ALDH1A1 (0.50) | NQO2TLR8NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257538-B1 | 9-ALKYLAMINO-1-NITROACRIDINE DERIVATIVES | NEW YORK MEDICAL COLLEGE (US) | 2010-09-08 | — | — | EP | disclosed |
| US-6589961-B2 | For inhibiting metastases of a tumor in a mammal | NEW YORK MEDICAL COLLEGE | 2003-07-08 | — | — | US | disclosed |
| EP-1257538-A2 | 9-ALKYLAMINO-1-NITROACRIDINE DERIVATIVES | NEW YORK MEDICAL COLLEGE (US) | 2002-11-20 | — | — | EP | disclosed |
| US-20020099211-A1 | 9-alkylamino-1-nitroacridine derivatives | NEW YORK MEDICAL COLLEGE | 2002-07-25 | — | — | US | disclosed |
| WO-2001060801-A2 | 9-ALKYLAMINO-1-NITROACRIDINE DERIVATIVES | NEW YORK MEDICAL COLLEGE (US) | 2001-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099211-A1 | 9-alkylamino-1-nitroacridine derivatives | NPPA, ABCB11, ABCC9 | NQO2 119/4885TLR8 599/4885NPC1 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.