Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.35 |
| ▸ | PPARD | Q03181 | 9/20 | 0.35 |
| ▸ | PPARA | Q07869 | 9/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | FABP4 | P15090 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9244452 | 0.89 | PPARG (0.37) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL9241981 | 0.84 | LMNA (0.35) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL8889904 | 0.83 | APEX1 (0.31) | APEX1 | |
| SCHEMBL8889911 | 0.83 | APEX1 (0.31) | APEX1 | |
| SCHEMBL8168806 | 0.80 | LMNA (0.36) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL4732244 | 0.79 | TSHR (0.34) | TSHRALDH1A1TDP1RECQLATM | |
| SCHEMBL7699787 | 0.76 | DGKA (0.47) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL11127758 | 0.76 | AKR1B1 (0.41) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL5463572 | 0.75 | DGKA (0.44) | TSHRALDH1A1ALOX15MAPTLMNA | |
| SCHEMBL5005110 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434362-B1 | Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution | TOMEI SANGYO KK (JP) | 1995-03-22 | — | — | EP | disclosed |
| EP-0433046-B1 | Polymer-type polymerization initiator | TOMEI SANGYO KK (JP) | 1994-08-10 | — | — | EP | disclosed |
| US-5206298-A | GRAFT COPOLYMER, SOLUTION CONTAINING THE GRAFT COPOLYMER FOR TREATING CONTACT LENS, AND METHOD OF TREATING CONTACT LENS WITH THE SOLUTION AND MAKING HYDROPHILIC LENS SURFACE | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1993-04-27 | — | — | US | disclosed |
| US-5134213-A | N-Vinyllactam-Monoperoxyfumarate Terpolymer | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1992-07-28 | — | — | US | disclosed |
| US-5082912-A | For graft polymerization, surfactants | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1992-01-21 | — | — | US | disclosed |
| EP-0434362-A1 | Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution | Tomei Sangyo Kabushiki Kaisha (JP) | 1991-06-26 | — | — | EP | disclosed |
| EP-0433046-A2 | Polymer-type polymerization initiator | Tomei Sangyo Kabushiki Kaisha (JP) | 1991-06-19 | — | — | EP | disclosed |