SCHEMBL9244452

SCHEMBL9244452

CCCCCCCCCCCCCCCCCCC(=CC(=O)O)C(=O)OOOC(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 9/20 0.37
PPARD Q03181 9/20 0.37
PPARA Q07869 9/20 0.37
GPR84 Q9NQS5 7/20 0.37
ALDH1A1 P00352 6/20 0.37
HDAC11 Q96DB2 5/20 0.37
TSHR P16473 5/20 0.37
PTPN1 P18031 3/20 0.37
TDP1 Q9NUW8 3/20 0.37
FABP4 P15090 3/20 0.37
ALOX15 P16050 3/20 0.37
HSD17B10 Q99714 3/20 0.37
TLR2 O60603 2/20 0.37
FFAR1 O14842 2/20 0.37
FFAR4 Q5NUL3 2/20 0.37
FABP3 P05413 2/20 0.37
SLC22A6 Q4U2R8 1/20 0.37
SLC22A8 Q8TCC7 1/20 0.37
MEN1 O00255 1/20 0.37
ESR1 P03372 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8889904 0.94 APEX1 (0.31) APEX1
SCHEMBL8889911 0.94 APEX1 (0.31) APEX1
SCHEMBL9240644 0.89 PPARG (0.35) PPARGPPARDPPARAGPR84ALDH1A1
SCHEMBL9241981 0.87 LMNA (0.35) PPARGPPARDPPARAGPR84ALDH1A1
SCHEMBL8889897 0.82 ALDH1A1 (0.31) ALDH1A1
SCHEMBL4732254 0.82 KDM4E (0.31) TSHRKDM4E
SCHEMBL17364123 0.82 KDM4E (0.31) TSHRKDM4E
SCHEMBL11127758 0.79 AKR1B1 (0.41) PPARGPPARDPPARAGPR84ALDH1A1
SCHEMBL4732188 0.78 TSHR (0.35) ALDH1A1TSHRTDP1LMNACYP3A4
SCHEMBL9150423 0.75 FAAH (0.53) PPARGPPARDPPARAGPR84ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434362-B1 Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution TOMEI SANGYO KK (JP) 1995-03-22 EP disclosed
EP-0433046-B1 Polymer-type polymerization initiator TOMEI SANGYO KK (JP) 1994-08-10 EP disclosed
US-5206298-A GRAFT COPOLYMER, SOLUTION CONTAINING THE GRAFT COPOLYMER FOR TREATING CONTACT LENS, AND METHOD OF TREATING CONTACT LENS WITH THE SOLUTION AND MAKING HYDROPHILIC LENS SURFACE TOMEI SANGYO KABUSHIKI KAISHA (JP) 1993-04-27 US disclosed
US-5134213-A N-Vinyllactam-Monoperoxyfumarate Terpolymer TOMEI SANGYO KABUSHIKI KAISHA (JP) 1992-07-28 US disclosed
US-5082912-A For graft polymerization, surfactants TOMEI SANGYO KABUSHIKI KAISHA (JP) 1992-01-21 US disclosed
EP-0434362-A1 Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution Tomei Sangyo Kabushiki Kaisha (JP) 1991-06-26 EP disclosed
EP-0433046-A2 Polymer-type polymerization initiator Tomei Sangyo Kabushiki Kaisha (JP) 1991-06-19 EP disclosed