Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732188 | 0.90 | TSHR (0.35) | TSHRRECQLCYP3A4ATMTDP1 | |
| SCHEMBL4783446 | 0.87 | TSHR (0.33) | TSHRRECQLCYP3A4ATMTDP1 | |
| SCHEMBL4729112 | 0.82 | ALDH1A1 (0.38) | CYP3A4CA2MAPK1ALDH1A1 | |
| SCHEMBL9240644 | 0.79 | PPARG (0.35) | TSHRRECQLATMTDP1ALDH1A1 | |
| SCHEMBL27619467 | 0.77 | TSHR (0.43) | TSHRRECQLCYP3A4ATMTDP1 | |
| SCHEMBL450703 | 0.76 | TSHR (0.52) | TSHRRECQLCYP3A4ATMTDP1 | |
| SCHEMBL2250221 | 0.74 | CA2 (0.43) | TSHRRECQLCYP3A4ATMTDP1 | |
| SCHEMBL9193145 | 0.74 | CA2 (0.43) | TSHRRECQLCYP3A4ATMTDP1 | |
| SCHEMBL183765 | 0.74 | CA2 (0.43) | TSHRRECQLCYP3A4ATMTDP1 | |
| SCHEMBL9241079 | 0.74 | TSHR (0.55) | TSHRRECQLCYP3A4ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080250739-A1 | FOAMED PLASTIC STRUCTURES | NOVA CHEMICALS INC. (US) | 2008-10-16 | — | — | US | disclosed |
| WO-2008057705-A1 | FOAMED PLASTIC STRUCTURES | NOVA CHEMICALS INC. (US) | 2008-05-15 | — | — | WO | disclosed |
| EP-0785964-B1 | NON-LINEAR STYRENIC POLYMER-BASED FOAMS | DOW CHEMICAL CO (US) | 1999-04-14 | — | — | EP | disclosed |
| US-5830924-A | LOW DENSITY CLOSED CELL, BLOWING AGENTS | THE DOW CHEMICAL COMPANY (US) | 1998-11-03 | — | — | US | disclosed |
| EP-0785957-B1 | NON-LINEAR STYRENIC POLYMER COMPOSITIONS AND ARTICLES PREPARED THEREFROM | DOW CHEMICAL CO (US) | 1998-05-20 | — | — | EP | disclosed |
| EP-0785957-A1 | NON-LINEAR STYRENIC POLYMER COMPOSITIONS AND ARTICLES PREPARED THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011962-A1 | NON-LINEAR STYRENIC POLYMER COMPOSITIONS AND ARTICLES PREPARED THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1996-04-25 | — | — | WO | disclosed |