SCHEMBL924221

SCHEMBL924221

Cc1ccc(Oc2cccc(C)c2O)cc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.44
ALDH1A1 P00352 3/20 0.43
HTR2A P28223 1/20 0.39
SLC6A4 P31645 1/20 0.39
AR P10275 2/20 0.38
POLB P06746 1/20 0.38
FFAR1 O14842 1/20 0.38
MAPT P10636 3/20 0.37
LMNA P02545 2/20 0.37
TP53 P04637 2/20 0.37
ALOX15 P16050 2/20 0.37
ALOX12 P18054 2/20 0.37
MAPK1 P28482 2/20 0.37
TSHR P16473 2/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP3A4 P08684 1/20 0.37
HPGD P15428 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CASP1 P29466 1/20 0.37
MEN1 O00255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL923048 0.86 TRPA1 (0.44) TRPA1ALDH1A1HTR2ASLC6A4AR
SCHEMBL10981342 0.80 ALDH1A1 (0.48) TRPA1ALDH1A1HTR2ASLC6A4POLB
SCHEMBL14707162 0.80 MEN1 (0.47) TRPA1ALDH1A1MAPTLMNATP53
SCHEMBL78097 0.79 TSHR (0.50) TRPA1ALDH1A1MAPTLMNAALOX15
SCHEMBL921819 0.79 ALDH1A1 (0.62) TRPA1ALDH1A1MAPTLMNATP53
SCHEMBL30358267 0.78 ALDH1A1 (0.50) TRPA1ALDH1A1SLC6A4POLBLMNA
SCHEMBL2913336 0.78 ALDH1A1 (0.50) TRPA1ALDH1A1SLC6A4POLBLMNA
SCHEMBL11125532 0.78 SLC6A4 (0.50) ALDH1A1HTR2ASLC6A4LMNA
SCHEMBL11124182 0.77 HTR2A (0.45) TRPA1ALDH1A1HTR2ASLC6A4LMNA
SCHEMBL29256758 0.74 LTA4H (0.59) ALDH1A1MAPTLMNAALOX12TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
US-7985522-B2 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2011-07-26 US disclosed
EP-1770447-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY MITSUBISHI CHEM CORP (JP) 2011-03-16 EP disclosed
US-20110013934-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2011-01-20 US disclosed
EP-2154575-A2 Electrophotographic photoreceptor Mitsubishi Chemical Corporation (JP) 2010-02-17 EP disclosed
US-7604913-B2 Electrophotographic photosensitive body MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-20 US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 US disclosed
US-20090047589-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-19 US disclosed
US-20080063963-A1 Electrophotographic Photosensitive Body MITSUBISHI CHEMICAL CORPORATION (JP) 2008-03-13 US disclosed
EP-1770447-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY Mitsubishi Chemical Corporation (JP) 2007-04-04 EP disclosed