Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11128666 | 0.76 | POLB (0.43) | POLBL3MBTL1NSD2ABL1PPARG | |
| SCHEMBL8370127 | 0.76 | LMNA (0.53) | POLBL3MBTL1NSD2ABL1PPARG | |
| SCHEMBL6256771 | 0.75 | L3MBTL1 (0.47) | POLBL3MBTL1NSD2ABL1PPARG | |
| SCHEMBL6216372 | 0.74 | MAOB (0.63) | POLBL3MBTL1NSD2ABL1PPARG | |
| SCHEMBL21295168 | 0.72 | HTR1A (0.61) | POLBL3MBTL1MAOBMEN1HPGD | |
| Benzylphenylether SCHEMBL3649694 | 0.71 | CA12 (0.62) | L3MBTL1MAOAMAOBHPGDSMN1; SMN2 | |
| SCHEMBL10803126 | 0.71 | MAPK14 (0.47) | L3MBTL1PPARGMAPK14MEN1HPGD | |
| SCHEMBL82673 | 0.70 | POLB (1.00) | POLBL3MBTL1NSD2ABL1PPARG | |
| SCHEMBL3044017 | 0.70 | HIF1A (0.48) | NSD2MAOAMAOBALDH1A1MEN1 | |
| SCHEMBL23259192 | 0.69 | PTGER1 (0.50) | L3MBTL1MAPK14ALDH1A1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446011-A | Imagewise coloring when heating; mixture of n-substituted indole, aromatic polyhydroxy compound, carbonyl compound and an acid | RICOH COMPANY, LTD. (JP) | 1995-08-29 | — | — | US | disclosed |