Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8824050 | 1.00 | HTR1A (0.45) | HTR1AHTR2AHTR7HTR6MEN1 | |
| SCHEMBL8824024 | 0.76 | ALDH1A2 (0.39) | MEN1KMT2AMAPTNPC1GAA | |
| SCHEMBL8824003 | 0.75 | HTT (0.38) | HTR1AHTR7MEN1KMT2AMAPT | |
| SCHEMBL8824004 | 0.75 | HTT (0.38) | HTR1AHTR7MEN1KMT2AMAPT | |
| SCHEMBL8824079 | 0.73 | PARP1 (0.48) | HTR1AHTR2AHTR7HTR6MEN1 | |
| SCHEMBL8824083 | 0.73 | PARP1 (0.48) | HTR1AHTR2AHTR7HTR6MEN1 | |
| SCHEMBL8824013 | 0.72 | KDM4E (0.34) | HTR1AHTR7MEN1KMT2AMAPT | |
| SCHEMBL9242129 | 0.72 | KDM4E (0.34) | HTR1AHTR7MEN1KMT2AMAPT | |
| SCHEMBL8824064 | 0.71 | KDM4E (0.40) | HTR1AMEN1KMT2AMAPTNPC1 | |
| SCHEMBL16913852 | 0.69 | ALDH1A1 (0.48) | HTR1AHTR2AHTR7HTR6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638570-A1 | TRICYCLIC COMPOUND HAVING ANTIALLERGIC EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |