Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252948 | 0.83 | CYP2D6 (0.39) | TSHRMAPTKMT2AALDH1A1 | |
| SCHEMBL9687859 | 0.76 | TSHR (0.46) | TSHRHPGDNPC1MAPTRAB9A | |
| SCHEMBL9251651 | 0.70 | TSHR (0.40) | TSHRHPGDNPC1MAPTRAB9A | |
| SCHEMBL9244665 | 0.69 | TRPA1 (0.37) | HPGD | |
| SCHEMBL19130232 | 0.67 | TSHR (0.50) | TSHRHPGDNPC1MAPTRAB9A | |
| SCHEMBL12238616 | 0.67 | TSHR (0.50) | TSHRHPGDNPC1MAPTRAB9A | |
| SCHEMBL9249701 | 0.67 | KCNN4 (0.33) | MEN1KMT2AALDH1A1 | |
| SCHEMBL28378957 | 0.65 | TSHR (0.46) | TSHRHPGDNPC1MAPTRAB9A | |
| SCHEMBL25489564 | 0.62 | TSHR (0.55) | TSHRNPC1MAPTRAB9ACYP19A1 | |
| SCHEMBL29096761 | 0.61 | TSHR (0.48) | TSHRNPC1MAPTRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399284-B1 | Method for the production of geminal diarylalkanes, geminal diarylalkanes and alk(en)ylated aromatic compounds | BAYER AG (DE) | 1995-08-02 | — | — | EP | disclosed |
| US-5136114-A | PROCESS FOR THE PREPARATION OF GEMINAL DIARYLALKANES, NEW GEMINAL DIARYLALKANES AND ALK(EN)YLATED AROMATIC COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0399284-A2 | Method for the production of geminal diarylalkanes, geminal diarylalkanes and alk(en)ylated aromatic compounds | BAYER AG (DE) | 1990-11-28 | — | — | EP | disclosed |