Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11044678 | 0.83 | MEN1 (0.52) | TSHRNPC1RAB9ACYP19A1MEN1 | |
| SCHEMBL9244761 | 0.80 | ALDH1A1 (0.41) | TSHRMAPTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9243122 | 0.76 | TSHR (0.40) | TSHRHPGDNPC1RAB9AMAPT | |
| SCHEMBL9251651 | 0.76 | TSHR (0.40) | TSHRHPGDNPC1RAB9AMAPT | |
| SCHEMBL11147182 | 0.75 | TSHR (0.43) | TSHRHPGDNPC1RAB9AMAPT | |
| SCHEMBL9250886 | 0.72 | TP53 (0.38) | NPC1RAB9AMAPTTDP1MEN1 | |
| SCHEMBL4969374 | 0.72 | TSHR (0.55) | TSHRHPGDNPC1RAB9AMAPT | |
| SCHEMBL9858415 | 0.70 | TSHR (0.52) | TSHRHPGDNPC1RAB9AMAPT | |
| SCHEMBL21147724 | 0.66 | ALDH1A1 (0.35) | TSHRHPGDNPC1RAB9AMAPT | |
| P-Xylene SCHEMBL11553864 | 0.66 | ACHE (0.80) | TSHRACHETDP1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5136114-A | PROCESS FOR THE PREPARATION OF GEMINAL DIARYLALKANES, NEW GEMINAL DIARYLALKANES AND ALK(EN)YLATED AROMATIC COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-04 | — | — | US | disclosed |