Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250883 | 0.80 | TRPA1 (0.42) | TRPA1ATMGABRA1GABRB2 | |
| SCHEMBL9249701 | 0.75 | KCNN4 (0.33) | — | |
| SCHEMBL9250735 | 0.74 | TRPA1 (0.37) | TRPA1ATMGABRA1GABRB2 | |
| SCHEMBL28650800 | 0.71 | TRPA1 (0.43) | TRPA1ATMGABRA1GABRB2 | |
| SCHEMBL9252948 | 0.70 | CYP2D6 (0.39) | TRPA1 | |
| SCHEMBL9243122 | 0.69 | TSHR (0.40) | HPGD | |
| SCHEMBL2422395 | 0.67 | TRPA1 (0.52) | TRPA1ATMGABRA1GABRB2 | |
| SCHEMBL9420693 | 0.67 | TRPA1 (0.46) | TRPA1ATMGABRA1GABRB2 | |
| SCHEMBL9065287 | 0.66 | TRPA1 (0.50) | TRPA1ATMGABRA1GABRB2 | |
| SCHEMBL3167832 | 0.66 | GABRA1 (0.60) | TRPA1ATMGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399284-B1 | Method for the production of geminal diarylalkanes, geminal diarylalkanes and alk(en)ylated aromatic compounds | BAYER AG (DE) | 1995-08-02 | — | — | EP | disclosed |
| US-5136114-A | PROCESS FOR THE PREPARATION OF GEMINAL DIARYLALKANES, NEW GEMINAL DIARYLALKANES AND ALK(EN)YLATED AROMATIC COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0399284-A2 | Method for the production of geminal diarylalkanes, geminal diarylalkanes and alk(en)ylated aromatic compounds | BAYER AG (DE) | 1990-11-28 | — | — | EP | disclosed |