Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9244665 | 0.75 | TRPA1 (0.37) | — | |
| SCHEMBL9252948 | 0.75 | CYP2D6 (0.39) | ALDH1A1ALOX15HDAC3HDAC1HDAC2 | |
| SCHEMBL9247990 | 0.74 | ALDH1A1 (0.37) | ALDH1A1ALOX15KMT2A | |
| SCHEMBL9963339 | 0.70 | ACHE (0.37) | KCNN4ALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL19448777 | 0.69 | KCNN4 (0.39) | KCNN4ALDH1A1ALOX15HDAC3HDAC1 | |
| SCHEMBL5682311 | 0.67 | KCNN4 (0.42) | KCNN4ALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL9243122 | 0.67 | TSHR (0.40) | ALDH1A1MEN1KMT2A | |
| SCHEMBL30603799 | 0.66 | KCNN4 (0.40) | KCNN4ALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL17080367 | 0.66 | KCNN4 (0.40) | KCNN4ALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL12557615 | 0.65 | ACHE (0.40) | KCNN4ALDH1A1ALOX15HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399284-B1 | Method for the production of geminal diarylalkanes, geminal diarylalkanes and alk(en)ylated aromatic compounds | BAYER AG (DE) | 1995-08-02 | — | — | EP | disclosed |
| US-5136114-A | PROCESS FOR THE PREPARATION OF GEMINAL DIARYLALKANES, NEW GEMINAL DIARYLALKANES AND ALK(EN)YLATED AROMATIC COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0399284-A2 | Method for the production of geminal diarylalkanes, geminal diarylalkanes and alk(en)ylated aromatic compounds | BAYER AG (DE) | 1990-11-28 | — | — | EP | disclosed |