Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9248905 | 0.96 | RAB9A (0.42) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9245612 | 0.91 | NPC1 (0.44) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9243119 | 0.89 | L3MBTL1 (0.41) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9249589 | 0.86 | GRM5 (0.50) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9243146 | 0.85 | KDM4E (0.39) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9246205 | 0.85 | RAB9A (0.40) | KDM4EALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL9245865 | 0.84 | MMP2 (0.39) | KDM4EALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL9241262 | 0.84 | MMP2 (0.39) | KDM4EALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL9247577 | 0.83 | L3MBTL1 (0.49) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9247783 | 0.83 | FFAR1 (0.45) | HSD17B10PDE5ACYP11B1CYP11B2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447657-A | Liquid crystal compounds | HOFFMANN-LA ROCHE INC. (US) | 1995-09-05 | — | — | US | disclosed |