Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 4/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 8/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9241946 | 1.00 | THRA (0.45) | THRATHRBMAOAMAOBPLK1 | |
| SCHEMBL7281456 | 1.00 | THRA (0.45) | THRATHRBMAOAMAOBPLK1 | |
| SCHEMBL7272059 | 1.00 | THRA (0.45) | THRATHRBMAOAMAOBPLK1 | |
| SCHEMBL5376643 | 1.00 | THRA (0.45) | THRATHRBMAOAMAOBPLK1 | |
| SCHEMBL11223570 | 1.00 | THRA (0.45) | THRATHRBMAOAMAOBPLK1 | |
| SCHEMBL11483343 | 1.00 | THRA (0.45) | THRATHRBMAOAMAOBPLK1 | |
| SCHEMBL5376886 | 0.98 | MAOA (0.43) | THRATHRBMAOAMAOBPLK1 | |
| SCHEMBL4469660 | 0.92 | MAOA (0.49) | THRATHRBMAOAMAOBSOAT1 | |
| SCHEMBL11569857 | 0.85 | THRB (0.56) | THRATHRBMAOAMAOBPLK1 | |
| SCHEMBL21575599 | 0.85 | THRB (0.56) | THRATHRBMAOAMAOBPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0437186-B1 | Melamine derivatives as stabilizers for chlorine containing polymers | CIBA GEIGY AG (CH) | 1995-12-06 | — | — | EP | disclosed |
| US-5272192-A | Melamine derivatives as stabilizers for chloride-containing polymers | CIBA-GEIGY CORPORATION (US) | 1993-12-21 | — | — | US | disclosed |
| EP-0437186-A1 | Melamine derivatives as stabilizers for chlorine containing polymers | CIBA-GEIGY AG (CH) | 1991-07-17 | — | — | EP | disclosed |