Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250886 | 0.80 | TP53 (0.38) | LMNAMAPTMEN1KMT2AGPR55 | |
| SCHEMBL9243122 | 0.76 | TSHR (0.40) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9250737 | 0.74 | CASR (0.33) | LMNAMAPTMEN1KMT2AGPR55 | |
| SCHEMBL9244665 | 0.74 | TRPA1 (0.37) | TRPA1 | |
| SCHEMBL9249701 | 0.69 | KCNN4 (0.33) | MEN1KMT2AALDH1A1 | |
| SCHEMBL18242406 | 0.68 | TDP1 (0.42) | LMNAMAPTMEN1KMT2AGPR55 | |
| SCHEMBL9252948 | 0.67 | CYP2D6 (0.39) | MAPTKMT2AALDH1A1TRPA1 | |
| SCHEMBL11501560 | 0.67 | TDP1 (0.41) | LMNAMAPTMEN1KMT2AGPR55 | |
| SCHEMBL18546040 | 0.67 | CASR (0.53) | LMNAMAPTMEN1KMT2AGPR55 | |
| SCHEMBL12180439 | 0.67 | TDP1 (0.46) | LMNAMAPTMEN1KMT2AGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399284-B1 | Method for the production of geminal diarylalkanes, geminal diarylalkanes and alk(en)ylated aromatic compounds | BAYER AG (DE) | 1995-08-02 | — | — | EP | disclosed |
| US-5136114-A | PROCESS FOR THE PREPARATION OF GEMINAL DIARYLALKANES, NEW GEMINAL DIARYLALKANES AND ALK(EN)YLATED AROMATIC COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0399284-A2 | Method for the production of geminal diarylalkanes, geminal diarylalkanes and alk(en)ylated aromatic compounds | BAYER AG (DE) | 1990-11-28 | — | — | EP | disclosed |