Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.69 |
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.69 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.50 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TDP2 | O95551 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NMT1 | P30419 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2429556 | 0.90 | ALDH1A1 (0.81) | ALDH1A1MAPTHTTDDAH1LPAR2 | |
| SCHEMBL8733897 | 0.83 | MAPT (0.71) | ALDH1A1MAPTHTTDDAH1LPAR2 | |
| SCHEMBL7771122 | 0.83 | MAPT (0.71) | ALDH1A1MAPTHTTDDAH1LPAR2 | |
| SCHEMBL5177391 | 0.81 | DDAH1 (1.00) | ALDH1A1MAPTHTTDDAH1LPAR2 | |
| SCHEMBL5177465 | 0.81 | DDAH1 (1.00) | ALDH1A1MAPTHTTDDAH1LPAR2 | |
| SCHEMBL15708801 | 0.81 | ALDH1A1 (0.69) | ALDH1A1MAPTHTTDDAH1LPAR2 | |
| SCHEMBL2682631 | 0.81 | MAPT (0.68) | ALDH1A1MAPTHTTDDAH1LPAR2 | |
| SCHEMBL5176397 | 0.81 | MAPT (0.68) | ALDH1A1MAPTHTTDDAH1LPAR2 | |
| SCHEMBL2682630 | 0.81 | MAPT (0.68) | ALDH1A1MAPTHTTDDAH1LPAR2 | |
| SCHEMBL5481885 | 0.77 | MAPT (0.63) | ALDH1A1MAPTHTTDDAH1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446106-A | Additional polymerizing a maleic anhydride with a dioxolane in presence of a free radical catalysts, futher reacting with primary amine | EASTMAN CHEMICAL COMPANY (US) | 1995-08-29 | — | — | US | disclosed |
| US-5418294-A | Clear films | EASTMAN CHEMICAL COMPANY (US) | 1995-05-23 | — | — | US | disclosed |
| WO-1994015976-A1 | COPOLYMERS OF VINYL DIOXOLANES AND IMIDIZED DERIVATIVES OF MALEIC ANHYDRIDE | EASTMAN CHEMICAL COMPANY (US) | 1994-07-21 | — | — | WO | disclosed |
| US-5304611-A | Can be cast as clear films or used as crosslinking agents | EASTMAN KODAK COMPANY (US) | 1994-04-19 | — | — | US | disclosed |