SCHEMBL9244759

SCHEMBL9244759

O=C(O)Oc1cccc(Cc2cccc(OC(=O)O)c2)c1

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ACHE P22303 5/20 0.46
KMT2A Q03164 3/20 0.46
PARP1 P09874 1/20 0.46
MEN1 O00255 1/20 0.45
CYP3A4 P08684 1/20 0.44
LMNA P02545 1/20 0.44
BCHE P06276 1/20 0.44
HRH1 P35367 1/20 0.43
CYP1A2 P05177 1/20 0.42
MTNR1A P48039 1/20 0.42
MTNR1B P49286 1/20 0.42
CFD P00746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28374506 0.86 TSHR (0.55) ACHEKMT2AMEN1CYP3A4LMNA
SCHEMBL28055585 0.83 ACHE (0.47) ACHEKMT2APARP1BCHEHRH1
SCHEMBL1040127 0.83 KMT2A (0.62) ACHEKMT2AMEN1CYP3A4LMNA
SCHEMBL28375781 0.80 SRD5A2 (0.50) ACHEKMT2ALMNABCHEHRH1
SCHEMBL28221521 0.79 ACHE (0.50) ACHEKMT2AMEN1BCHEMTNR1A
SCHEMBL10891821 0.79 THRB (0.47) ACHEKMT2APARP1BCHEHRH1
SCHEMBL27564217 0.79 ACHE (0.56) ACHEKMT2AMEN1LMNABCHE
SCHEMBL7371530 0.79 CYP4F2 (0.40) KMT2AMEN1CYP3A4LMNACFD
SCHEMBL28040668 0.78 KMT2A (0.56) ACHEKMT2AMEN1
SCHEMBL6224844 0.78 LTA4H (0.55) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0472168-B1 Allyl ester oligomer composition and organic glass for optical material comprising same SHOWA DENKO KK (JP) 1995-08-02 EP claimed
EP-3512905-A1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2019-07-24 EP disclosed
WO-2018050489-A1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2018-03-22 WO disclosed
EP-0432095-A1 Anthraquino vat dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1991-06-12 EP disclosed
EP-0274458-B1 ANTHRAQUINONE VAT DYESTUFFS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1990-09-19 EP disclosed