Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9245836 | 0.81 | PTGS2 (0.40) | PTGS2CYP3A4TDP1MEN1KMT2A | |
| SCHEMBL9136370 | 0.68 | KCNH2 (0.44) | PTGS2CYP3A4TDP1L3MBTL1KCNH2 | |
| SCHEMBL16204102 | 0.67 | KCNH2 (0.39) | PTGS2KCNH2GPR84 | |
| Bromide SCHEMBL25430864 | 0.67 | ALDH1A1 (0.35) | PTGS2CYP3A4TDP1L3MBTL1KCNH2 | |
| SCHEMBL10843796 | 0.67 | KCNH2 (0.47) | PTGS2CYP3A4TDP1L3MBTL1KCNH2 | |
| SCHEMBL286920 | 0.66 | TLR8 (0.54) | TDP1KCNH2 | |
| SCHEMBL28468210 | 0.66 | ALOX5 (0.44) | PTGS2CYP3A4TDP1MEN1KMT2A | |
| SCHEMBL15967965 | 0.65 | KCNH2 (0.46) | PTGS2CYP3A4TDP1L3MBTL1KCNH2 | |
| SCHEMBL8979881 | 0.65 | KCNH2 (0.46) | PTGS2CYP3A4TDP1L3MBTL1KCNH2 | |
| SCHEMBL1228572 | 0.65 | HCAR2 (0.37) | TDP1L3MBTL1KCNH2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5462914-A | Reacting a hydroxypyridazine salt with a cyanogen halide | SANDOZ LTD. (CH) | 1995-10-31 | — | — | US | disclosed |
| EP-0556647-A1 | N-cyanopyridazinones as herbicides | SANDOZ LTD. (CH) | 1993-08-25 | — | — | EP | disclosed |