Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 2/20 | 0.31 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 known ✓ | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.31 |
| ▸ | ADRB3 known ✓ | P13945 | 1/20 | 0.31 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.31 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.31 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.31 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29151924 | 0.98 | ALDH1A1 (0.36) | ALDH1A1KCNH2MEN1KMT2ATSHR | |
| SCHEMBL3265562 | 0.80 | MEN1 (0.39) | ALDH1A1KCNH2MEN1KMT2ATSHR | |
| SCHEMBL27705339 | 0.73 | ALDH1A1 (0.36) | ALDH1A1KCNH2MEN1KMT2ATSHR | |
| SCHEMBL28529359 | 0.73 | LMNA (0.37) | ALDH1A1KCNH2MEN1KMT2ATSHR | |
| Iodide SCHEMBL27475412 | 0.72 | ALDH1A1 (0.35) | ALDH1A1KCNH2MEN1KMT2ATSHR | |
| SCHEMBL8027987 | 0.71 | ALDH1A1 (0.46) | ALDH1A1KCNH2MEN1KMT2ATSHR | |
| SCHEMBL440580 | 0.70 | TYR (0.37) | ALDH1A1KCNH2MEN1KMT2ATDP1 | |
| SCHEMBL1301339 | 0.68 | TDP1 (0.36) | ALDH1A1KCNH2MEN1KMT2ATSHR | |
| SCHEMBL28572772 | 0.68 | ALDH1A1 (0.35) | ALDH1A1KCNH2MEN1KMT2ATSHR | |
| SCHEMBL9244877 | 0.67 | PTGS2 (0.34) | ALDH1A1KCNH2MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250248296-A1 | DEFECT ENGINEERING IN WIDE BANDGAP PEROVSKITES FOR EFFICIENT AND STABLE FULLY TEXTURED PEROVSKITE-SILICON TANDEM SOLAR CELLS | UNITED STATES DEPARTMENT OF ENERGY | 2025-07-31 | — | — | US | claimed |
| WO-2023147338-A2 | DEFECT ENGINEERING IN WIDE BANDGAP PEROVSKITES FOR EFFICIENT AND STABLE FULLY TEXTURED PEROVSKITE-SILICON TANDEM SOLAR CELLS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-08-03 | — | — | WO | claimed |
| US-20250248296-A1 | DEFECT ENGINEERING IN WIDE BANDGAP PEROVSKITES FOR EFFICIENT AND STABLE FULLY TEXTURED PEROVSKITE-SILICON TANDEM SOLAR CELLS | UNITED STATES DEPARTMENT OF ENERGY | 2025-07-31 | — | — | US | disclosed |
| CN-117659071-A | Copper-doped aluminum oxide cluster layered material and preparation method and application thereof | 中国科学院福建物质结构研究所 | 2024-03-08 | — | — | CN | disclosed |
| WO-2023147338-A2 | DEFECT ENGINEERING IN WIDE BANDGAP PEROVSKITES FOR EFFICIENT AND STABLE FULLY TEXTURED PEROVSKITE-SILICON TANDEM SOLAR CELLS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-08-03 | — | — | WO | disclosed |
| CN-112094810-B | Single B cell screening method and application thereof in preparation of small molecule monoclonal antibody | 中国农业大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-112094810-A | Single B cell screening method and application thereof in preparation of small molecule monoclonal antibody | 中国农业大学 | 2020-12-18 | — | — | CN | disclosed |