Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9241262 | 0.99 | MMP2 (0.39) | RAB9ANPC1SMN1; SMN2HSD17B10PDE5A | |
| SCHEMBL9245865 | 0.99 | MMP2 (0.39) | RAB9ANPC1SMN1; SMN2HSD17B10PDE5A | |
| SCHEMBL9249847 | 0.96 | NPC1 (0.40) | RAB9ANPC1SMN1; SMN2HSD17B10PDE5A | |
| SCHEMBL8212860 | 0.91 | CYP2D6 (0.37) | RAB9ANPC1SMN1; SMN2HSD17B10PDE5A | |
| SCHEMBL9249535 | 0.89 | RAB9A (0.40) | RAB9ANPC1SMN1; SMN2HSD17B10MMP2 | |
| SCHEMBL9248027 | 0.88 | RAB9A (0.39) | RAB9ANPC1SMN1; SMN2HSD17B10MMP2 | |
| SCHEMBL9247851 | 0.85 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2HSD17B10MMP2 | |
| SCHEMBL9249291 | 0.85 | PDGFRB (0.37) | RAB9ANPC1SMN1; SMN2HSD17B10USP2 | |
| SCHEMBL9245766 | 0.85 | CHRNB2 (0.36) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9247471 | 0.85 | NPC1 (0.41) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447657-A | Liquid crystal compounds | HOFFMANN-LA ROCHE INC. (US) | 1995-09-05 | — | — | US | disclosed |