Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8212860 | 0.88 | CYP2D6 (0.37) | PDGFRBPDGFRAUSP7HSD17B10NPC1 | |
| SCHEMBL9249847 | 0.86 | NPC1 (0.40) | PDGFRBPDGFRAHSD17B10NPC1RAB9A | |
| SCHEMBL9246205 | 0.85 | RAB9A (0.40) | PDGFRBPDGFRAHSD17B10NPC1RAB9A | |
| SCHEMBL9241262 | 0.84 | MMP2 (0.39) | HSD17B10NPC1RAB9ASMN1; SMN2GRM5 | |
| SCHEMBL9245865 | 0.84 | MMP2 (0.39) | HSD17B10NPC1RAB9ASMN1; SMN2GRM5 | |
| SCHEMBL9248310 | 0.76 | NPC1 (0.37) | HSD17B10NPC1RAB9ASMN1; SMN2KMO | |
| SCHEMBL10719819 | 0.76 | GRIN2B (0.43) | PDGFRBPDGFRAUSP7HSD17B10NPC1 | |
| SCHEMBL14819075 | 0.75 | GRM5 (0.43) | GRM5 | |
| SCHEMBL9246705 | 0.74 | NPY5R (0.31) | GRIN2BOPRL1GRIN1 | |
| SCHEMBL9246715 | 0.74 | NPY5R (0.31) | GRIN2BOPRL1GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447657-A | Liquid crystal compounds | HOFFMANN-LA ROCHE INC. (US) | 1995-09-05 | — | — | US | disclosed |