Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9243003 | 0.80 | KDM1A (0.41) | SMN1; SMN2KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL19903965 | 0.74 | ALDH1A1 (0.48) | SMN1; SMN2KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL23458240 | 0.74 | ALDH1A1 (0.48) | SMN1; SMN2KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL9493702 | 0.74 | ALDH1A1 (0.48) | SMN1; SMN2KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL9493698 | 0.74 | ALDH1A1 (0.48) | SMN1; SMN2KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL15784372 | 0.71 | TDP1 (0.37) | SMN1; SMN2KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL6546277 | 0.71 | TRPA1 (0.51) | SMN1; SMN2KMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL18618524 | 0.70 | ALDH1A1 (0.44) | SMN1; SMN2KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL8670406 | 0.70 | ALDH1A1 (0.44) | SMN1; SMN2KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL20179477 | 0.70 | ALDH1A1 (0.44) | SMN1; SMN2KMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399284-B1 | Method for the production of geminal diarylalkanes, geminal diarylalkanes and alk(en)ylated aromatic compounds | BAYER AG (DE) | 1995-08-02 | — | — | EP | disclosed |
| US-5136114-A | PROCESS FOR THE PREPARATION OF GEMINAL DIARYLALKANES, NEW GEMINAL DIARYLALKANES AND ALK(EN)YLATED AROMATIC COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0399284-A2 | Method for the production of geminal diarylalkanes, geminal diarylalkanes and alk(en)ylated aromatic compounds | BAYER AG (DE) | 1990-11-28 | — | — | EP | disclosed |