Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | MC5R | P33032 | 1/20 | 0.32 |
| ▸ | MC3R | P41968 | 1/20 | 0.32 |
| ▸ | VDR | P11473 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250975 | 0.87 | FFAR1 (0.40) | HRH3SYKSPHK1 | |
| SCHEMBL9259393 | 0.76 | ITGB3 (0.39) | ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9408001 | 0.72 | ITGB3 (0.41) | HRH3CTSDEPHX2 | |
| SCHEMBL9568559 | 0.71 | F2 (0.41) | HDAC1 | |
| SCHEMBL9257084 | 0.71 | F2 (0.41) | HDAC1 | |
| Hydrochloric Acid SCHEMBL9254356 | 0.70 | F2 (0.40) | HDAC1 | |
| SCHEMBL9257792 | 0.70 | CYP11B1 (0.47) | HRH3HDAC1ALDH1A1MAPT | |
| SCHEMBL440195 | 0.69 | TDP1 (0.43) | ALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL9250343 | 0.68 | HDAC1 (0.41) | HRH3CTSDHDAC1MAPTVDR | |
| SCHEMBL9259285 | 0.67 | HRH3 (0.35) | HRH3HDAC1ALDH1A1HPGDADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |