Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.57 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.57 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.57 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 10/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.43 |
| ▸ | LMNA | P02545 | 9/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | CCR6 | P51684 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14313792 | 0.85 | FGFR1 (0.50) | FGFR1FGFR2FGFR4FGFR3MAPT | |
| SCHEMBL9628254 | 0.77 | MAPT (0.65) | FGFR1FGFR2FGFR4FGFR3MAPT | |
| SCHEMBL9627536 | 0.77 | CDC25B (0.53) | FGFR1FGFR2FGFR4FGFR3MAPT | |
| SCHEMBL30004167 | 0.75 | FGFR1 (0.57) | FGFR1FGFR2FGFR4FGFR3MAPT | |
| SCHEMBL5820931 | 0.75 | FGFR1 (0.57) | FGFR1FGFR2FGFR4FGFR3MAPT | |
| SCHEMBL21814476 | 0.74 | FGFR1 (0.53) | FGFR1FGFR2FGFR4FGFR3MAPT | |
| SCHEMBL9627133 | 0.74 | PTPN1 (0.46) | FGFR1FGFR2FGFR4FGFR3MAPT | |
| SCHEMBL9627522 | 0.74 | MAPT (0.45) | FGFR1FGFR2FGFR4FGFR3MAPT | |
| SCHEMBL9713842 | 0.72 | HKDC1 (0.56) | FGFR1FGFR2FGFR4FGFR3MAPT | |
| SCHEMBL9627657 | 0.72 | PTPN1 (0.53) | FGFR1FGFR2FGFR4FGFR3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634996-A1 | 1,4 NAPHTHOQUINONE DERIVTIVES WITH ANTI-PROTOZOAL AND ANTI-PARASITIC ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-01-25 | — | — | EP | disclosed |