SCHEMBL9247488

SCHEMBL9247488

CCCCC(C)(OO)c1ccc(C(C)(C)C)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.43
ESR2 Q92731 4/20 0.43
HDAC3 O15379 2/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC2 Q92769 2/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
LMNA P02545 2/20 0.39
TYR P14679 1/20 0.39
HSD17B10 Q99714 1/20 0.38
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
STS P08842 2/20 0.36
TSHR P16473 1/20 0.35
BCHE P06276 3/20 0.34
ACHE P22303 3/20 0.34
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9240881 0.89 SMN1; SMN2 (0.42) ESR1ESR2HDAC3HDAC1HDAC2
SCHEMBL27998616 0.80 ALDH1A1 (0.47) MEN1ALDH1A1KMT2ACNR2
SCHEMBL8971230 0.79 ALDH1A1 (0.46) LMNAMEN1ALDH1A1KMT2ATSHR
SCHEMBL1581689 0.79 ALDH1A1 (0.46) LMNAMEN1ALDH1A1KMT2ATSHR
SCHEMBL26592454 0.72 ESR1 (0.40) ESR1ESR2HDAC3HDAC1HDAC2
SCHEMBL21681665 0.71 MAPK1 (0.41) ESR1ESR2ALDH1A1
SCHEMBL22908279 0.70 LMNA (0.40) ESR1ESR2HDAC3HDAC1HDAC2
SCHEMBL11765945 0.69 SIGMAR1 (0.54) ESR1ESR2SMN1; SMN2LMNAMEN1
SCHEMBL22334756 0.69 KMT2A (0.47) ESR1SMN1; SMN2LMNAHSD17B10ALDH1A1
SCHEMBL9593021 0.68 HRH3 (0.57) SMN1; SMN2LMNAHSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5446227-A Contacting alpha-methyl benzylic hydroperoxide with organic sulfide to produce corresponding hydroxide and oxygenated sulfur compound, treating hydroxide with base PHILLIPS PETROLEUM COMPANY (US) 1995-08-29 US claimed
US-5446227-A Contacting alpha-methyl benzylic hydroperoxide with organic sulfide to produce corresponding hydroxide and oxygenated sulfur compound, treating hydroxide with base PHILLIPS PETROLEUM COMPANY (US) 1995-08-29 US disclosed