Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9249654 | 0.80 | TDP1 (0.34) | CASRTP53TDP1 | |
| SCHEMBL9246395 | 0.75 | MAPT (0.33) | CASRTP53TDP1 | |
| SCHEMBL11501560 | 0.73 | TDP1 (0.41) | CASRTP53TDP1 | |
| SCHEMBL9247969 | 0.72 | TRPA1 (0.35) | — | |
| SCHEMBL28027575 | 0.71 | TDP1 (0.42) | CASRTP53TDP1 | |
| SCHEMBL9943563 | 0.71 | TDP1 (0.42) | CASRTP53TDP1 | |
| SCHEMBL9220402 | 0.71 | CASR (0.41) | CASRTP53TDP1PDE2A | |
| SCHEMBL12525117 | 0.68 | TP53 (0.41) | CASRTP53TDP1 | |
| SCHEMBL14430162 | 0.68 | TDP1 (0.37) | CASRTP53TDP1PDE2A | |
| SCHEMBL9210994 | 0.68 | ALDH1A1 (0.37) | CASRTP53TDP1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399284-B1 | Method for the production of geminal diarylalkanes, geminal diarylalkanes and alk(en)ylated aromatic compounds | BAYER AG (DE) | 1995-08-02 | — | — | EP | disclosed |
| US-5136114-A | PROCESS FOR THE PREPARATION OF GEMINAL DIARYLALKANES, NEW GEMINAL DIARYLALKANES AND ALK(EN)YLATED AROMATIC COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0399284-A2 | Method for the production of geminal diarylalkanes, geminal diarylalkanes and alk(en)ylated aromatic compounds | BAYER AG (DE) | 1990-11-28 | — | — | EP | disclosed |