Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.68 |
| ▸ | DRD3 | P35462 | 4/20 | 0.68 |
| ▸ | ACHE | P22303 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256276 | 0.92 | DRD2 (0.81) | DRD2DRD3ACHEMAOBADRA1A | |
| SCHEMBL9258386 | 0.92 | DRD2 (0.77) | DRD2DRD3ACHEALDH1A1POLB | |
| SCHEMBL9256958 | 0.91 | DRD2 (0.79) | DRD2DRD3ACHEMAOBADRA1A | |
| SCHEMBL31232750 | 0.89 | DRD2 (0.84) | DRD2DRD3ALDH1A1POLBGAA | |
| SCHEMBL9733689 | 0.89 | DRD2 (0.84) | DRD2DRD3ALDH1A1POLBGAA | |
| SCHEMBL9250459 | 0.88 | DRD2 (0.54) | DRD2DRD3ACHEALDH1A1POLB | |
| SCHEMBL9257199 | 0.85 | DRD3 (0.86) | DRD2DRD3ALDH1A1POLBGAA | |
| SCHEMBL9249351 | 0.82 | DRD2 (0.73) | DRD2DRD3ALDH1A1POLBGAA | |
| SCHEMBL7976323 | 0.81 | DRD2 (0.95) | DRD2DRD3ALDH1A1POLBGAA | |
| SCHEMBL9256633 | 0.81 | DRD2 (1.00) | DRD2DRD3ALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |