Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3160237 | 0.87 | ALDH1A1 (0.48) | CYP4F2CYP4A11CYP1A2ABCB11CYP3A4 | |
| SCHEMBL7098775 | 0.81 | ALOX15 (0.41) | CYP4F2CYP4A11DGAT1CYP1A2ABCB11 | |
| SCHEMBL9248229 | 0.76 | DGAT1 (0.60) | DGAT1 | |
| SCHEMBL3314455 | 0.76 | ALDH1A1 (0.46) | CYP4F2CYP4A11CYP1A2ABCB11CYP3A4 | |
| SCHEMBL8849154 | 0.76 | ALDH1A1 (0.42) | CYP4F2CYP4A11CYP1A2ABCB11CYP3A4 | |
| SCHEMBL18630791 | 0.75 | MMP8 (0.41) | CYP4F2CYP4A11DGAT1CYP1A2ABCB11 | |
| SCHEMBL21064825 | 0.75 | MEN1 (0.44) | CYP4F2CYP4A11DGAT1CYP1A2ABCB11 | |
| SCHEMBL18630793 | 0.75 | MMP8 (0.41) | CYP4F2CYP4A11DGAT1CYP1A2ABCB11 | |
| SCHEMBL11549163 | 0.75 | CYP4F2 (0.39) | CYP4F2CYP4A11DGAT1CYP1A2ABCB11 | |
| SCHEMBL28230745 | 0.75 | ALDH1A1 (0.37) | CYP4F2CYP4A11CYP1A2ABCB11CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687665-A1 | Process for preparing 2,2-dichloro-malonic acid esters | HÜLS AKTIENGESELLSCHAFT (DE) | 1995-12-20 | — | — | EP | disclosed |