Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | ME2 | P23368 | 1/20 | 0.51 |
| ▸ | ME1 | P48163 | 1/20 | 0.51 |
| ▸ | ME3 | Q16798 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL313151 | 0.86 | MEN1 (0.66) | MEN1KMT2AKDM4ECYP1A2ALDH1A1 | |
| SCHEMBL897604 | 0.84 | MEN1 (0.63) | MEN1KMT2AKDM4ECYP1A2ALDH1A1 | |
| SCHEMBL28080648 | 0.82 | HPGD (0.47) | MEN1KMT2AKDM4ECYP1A2ALDH1A1 | |
| SCHEMBL28751492 | 0.81 | MEN1 (0.59) | MEN1KMT2AKDM4ECYP1A2ALDH1A1 | |
| SCHEMBL6844838 | 0.81 | KDM4E (0.53) | MEN1KMT2AKDM4ECYP1A2ALDH1A1 | |
| SCHEMBL2880041 | 0.79 | MEN1 (0.56) | MEN1KMT2AKDM4ECYP1A2ALDH1A1 | |
| SCHEMBL28051080 | 0.78 | MEN1 (0.54) | MEN1KMT2AKDM4ECYP1A2ALDH1A1 | |
| SCHEMBL4731723 | 0.77 | ME2 (0.73) | MEN1KMT2AKDM4ECYP1A2ALDH1A1 | |
| Anthracene-9-Carboxylic Acid SCHEMBL122832 | 0.77 | MEN1 (1.00) | MEN1KMT2AKDM4ECYP1A2ALDH1A1 | |
| Anthracene-9-Carboxylic Acid SCHEMBL29352186 | 0.77 | MEN1 (1.00) | MEN1KMT2AKDM4ECYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0666849-A4 | ARYL AND HETEROARYLMETHOXYPHENYL INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS. | ABBOTT LAB (US) | 1995-12-13 | — | — | EP | disclosed |
| EP-0666849-A1 | ARYL AND HETEROARYLMETHOXYPHENYL INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1995-08-16 | — | — | EP | disclosed |
| WO-1994010148-A1 | ARYL AND HETEROARYLMETHOXYPHENYL INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1994-05-11 | — | — | WO | disclosed |