SCHEMBL2880041

SCHEMBL2880041

C=CCc1cc2ccccc2c(C(=O)O)c1C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
ALDH1A1 P00352 3/20 0.56
HPGD P15428 2/20 0.56
KDM4E B2RXH2 1/20 0.56
CYP1A2 P05177 1/20 0.56
GLA P06280 1/20 0.56
CYP2C19 P33261 1/20 0.56
HSD17B10 Q99714 1/20 0.56
ME2 P23368 1/20 0.48
ME1 P48163 1/20 0.48
ME3 Q16798 1/20 0.48
POLB P06746 2/20 0.39
GPR35 Q9HC97 2/20 0.39
MAPT P10636 1/20 0.38
CDC25B P30305 2/20 0.38
RXFP1 Q9HBX9 1/20 0.38
CYP2D6 P10635 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
NR4A1 P22736 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7396868 0.89 ME2 (0.57) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL497956 0.88 MEN1 (0.53) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL9741180 0.88 ME2 (0.49) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL28051080 0.83 MEN1 (0.54) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL487677 0.83 KDM4E (0.49) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL9062210 0.82 ALDH1A1 (0.41) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL313151 0.82 MEN1 (0.66) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL22160243 0.81 HMGB1 (0.44) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL29793830 0.81 HMGB1 (0.44) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL897604 0.80 MEN1 (0.63) MEN1KMT2AALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10053786-A None JP disclosed
CN-1900824-B Coating compositions for use with an overcoated photoresist ROHM & HAAS ELECT MAT 2011-09-14 CN disclosed
WO-2010013347-A1 LIQUID FOR LIQUID LENS AND LIQUID LENS JSR株式会社 (JP) 2010-02-04 WO disclosed
US-7204975-B2 Cosmetic and dermatological light-protective formulations with a content of particulate UV-filter substances and alkylnaphthalates BEIERSDORF AG (DE) 2007-04-17 US disclosed
US-7204973-B2 Cosmetic and dermatological light protection formulations with a content of hydroxybenzophenones and alkylnaphthalates BEIERSDORF AG (DE) 2007-04-17 US disclosed
EP-1127568-B1 Cosmetic and dermatological light protective formulations containing benzotriazole derivatives and alkylnaphthalates BEIERSDORF AG (DE) 2007-01-24 EP disclosed
CN-1900824-A Coating compositions for use with an overcoated photoresist ROHM & HAAS ELECT MAT (US) 2007-01-24 CN disclosed
EP-1127569-B1 Cosmetic and dermatological light protective formulations containing asymmetrically substituted triazine derivatives and alkylnaphthalates BEIERSDORF AG (DE) 2007-01-03 EP disclosed
US-20050129631-A1 Cosmetic and dermatological light protection formulations with a content of hydroxybenzophenones and alkylnaphthalates BEIERSDORF AG (DE) 2005-06-16 US disclosed
US-20040258638-A1 Cosmetic and dermatological light-protective formulations with a content of particulate UV-filter substances and alkylnaphthalates BEIERSDORF AG 2004-12-23 US disclosed
US-20040247540-A1 Containing as a stabilizer a di(C 6-24 branched or unbranched alkyl) 2,6-naphthalenedicarboxylate and a water-soluble UV filter for use in cosmetic or dermatological formulations. BEIERSDORF AG 2004-12-09 US disclosed
EP-1127568-A3 Cosmetic and dermatological light protective formulations containing benzotriazole derivatives and alkylnaphthalates Beiersdorf AG (DE) 2003-11-12 EP disclosed
EP-1127569-A3 Cosmetic and dermatological light protective formulations containing asymmetrically substituted triazine derivatives and alkylnaphthalates Beiersdorf AG (DE) 2003-11-12 EP disclosed
EP-1172425-A1 Outdoor durable coating composition DSM N.V. (NL) 2002-01-16 EP disclosed
EP-1127568-A2 Cosmetic and dermatological light protective formulations containing benzotriazole derivatives and alkylnaphthalates Beiersdorf AG (DE) 2001-08-29 EP disclosed
EP-1127569-A2 Cosmetic and dermatological light protective formulations containing asymmetrically substituted triazine derivatives and alkylnaphthalates Beiersdorf AG (DE) 2001-08-29 EP disclosed
WO-2000031584-A2 LIQUID COMPOSITION POLYMERIZABLE INTO ORGANIC GLASSES WITH A HIGH REFRACTIVE INDEX GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2000-06-02 WO disclosed
JP-H1053786-A SYNTHETIC LUBRICATING OIL COMPOSITION NKK CORP 1998-02-24 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040258638-A1 Cosmetic and dermatological light-protective formulations with a content of particulate UV-filter substances and alkylnaphthalates ERCC4, ERCC1, CUTA MEN1 2272/4885KMT2A 4059/4885ALDH1A1 104/4885
US-20050129631-A1 Cosmetic and dermatological light protection formulations with a content of hydroxybenzophenones and alkylnaphthalates TYR, AHR, CYP1B1 MEN1 1808/4885KMT2A 2935/4885ALDH1A1 50/4885
US-20040247540-A1 Containing as a stabilizer a di(C 6-24 branched or unbranched alkyl) 2,6-naphthalenedicarboxylate and a water-soluble UV filter for use in cosmetic or dermatological formulations. DHCR24, CUTA, ERCC1 MEN1 3429/4885KMT2A 3565/4885ALDH1A1 256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.