Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS15 | P98073 | 6/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.34 |
| ▸ | F10 | P00742 | 4/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258892 | 0.91 | ITGB3 (0.39) | ITGB3ITGA2BADORA3F10KDM4E | |
| SCHEMBL9258704 | 0.90 | HDAC1 (0.40) | ITGB3ITGA2BF10HDAC1F2 | |
| SCHEMBL9252190 | 0.88 | F10 (0.37) | TMPRSS15ITGB3ITGA2BF10CCNC | |
| SCHEMBL9253817 | 0.87 | TMPRSS15 (0.38) | TMPRSS15ITGB3ITGA2BF10CCNC | |
| SCHEMBL9251429 | 0.87 | TMPRSS15 (0.36) | TMPRSS15ITGB3ITGA2BF10HDAC1 | |
| SCHEMBL9250408 | 0.86 | CHEK1 (0.38) | TMPRSS15ITGB3ITGA2BADORA3CCNC | |
| SCHEMBL9254513 | 0.84 | CHEK1 (0.40) | TMPRSS15ITGB3ITGA2BPRSS1MEN1 | |
| SCHEMBL9257084 | 0.81 | F2 (0.41) | TMPRSS15ITGB3ITGA2BF10HDAC1 | |
| SCHEMBL9568559 | 0.81 | F2 (0.41) | TMPRSS15ITGB3ITGA2BF10HDAC1 | |
| Hydrochloric Acid SCHEMBL9254356 | 0.81 | F2 (0.40) | TMPRSS15ITGB3ITGA2BF10HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |