Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 4/20 | 0.37 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254909 | 0.91 | ITGB3 (0.45) | HDAC1F10F2HDAC2NPC1 | |
| SCHEMBL9568476 | 0.90 | TMPRSS15 (0.34) | HDAC1F10F2ITGB3ITGA2B | |
| SCHEMBL9252190 | 0.84 | F10 (0.37) | F10F2ITGB3ITGA2BPRSS1 | |
| SCHEMBL9253817 | 0.84 | TMPRSS15 (0.38) | F10F2ITGB3ITGA2BPRSS1 | |
| SCHEMBL9251429 | 0.84 | TMPRSS15 (0.36) | HDAC1F10F2ITGB3ITGA2B | |
| SCHEMBL9250408 | 0.83 | CHEK1 (0.38) | ITGB3ITGA2BMAPT | |
| SCHEMBL9258892 | 0.82 | ITGB3 (0.39) | F10ITGB3ITGA2BMAPTTYMS | |
| SCHEMBL9254513 | 0.81 | CHEK1 (0.40) | ITGB3ITGA2BPRSS1 | |
| SCHEMBL9257084 | 0.79 | F2 (0.41) | HDAC1F10F2ITGB3ITGA2B | |
| SCHEMBL9568559 | 0.79 | F2 (0.41) | HDAC1F10F2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |