Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.40 |
| ▸ | WNT1 | P04628 | 2/20 | 0.40 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9266551 | 0.89 | PLK1 (0.45) | KDM1AGSK3BDYRK1AWNT1IP6K1 | |
| SCHEMBL9262615 | 0.88 | KDM1A (0.42) | KDM1AGSK3BDYRK1AWNT1ROCK1 | |
| SCHEMBL9265566 | 0.85 | HPGDS (0.45) | KDM1AGSK3BDYRK1AWNT1EGLN1 | |
| SCHEMBL8535761 | 0.85 | PIK3CD (0.43) | — | |
| SCHEMBL9253063 | 0.84 | KDM1A (0.45) | KDM1AGSK3BDYRK1AWNT1MAOA | |
| SCHEMBL8531382 | 0.84 | GPR119 (0.43) | SCN9AACACB | |
| SCHEMBL9259070 | 0.83 | DYRK1A (0.44) | KDM1AGSK3BDYRK1AWNT1MAOA | |
| SCHEMBL8535759 | 0.82 | SCN9A (0.38) | SCN9AROCK1HPGDSCSF1RFLT3 | |
| SCHEMBL9261132 | 0.81 | GSK3B (0.41) | KDM1AGSK3BDYRK1AWNT1MAOA | |
| SCHEMBL9250864 | 0.80 | HRH3 (0.46) | KDM1AGSK3BDYRK1AWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069917-A1 | BICYCLIC GPR119 MODULATORS | LUPIN LIMITED (IN) | 2012-05-31 | — | — | WO | disclosed |